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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
13.33
Human Site:
S1517
Identified Species:
22.56
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
S1517
L
R
H
F
K
F
L
S
V
S
F
M
S
Q
L
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
S1517
L
R
H
F
K
F
L
S
V
S
F
M
S
Q
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
V1517
R
H
L
K
F
L
S
V
S
F
M
S
Q
L
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
V1517
R
H
F
K
Y
L
S
V
S
F
M
S
Q
L
L
Rat
Rattus norvegicus
NP_001101888
2143
241191
V1517
R
H
F
K
Y
L
S
V
S
F
M
A
Q
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
S1529
L
R
H
F
K
Y
L
S
V
S
F
M
S
Q
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
K1512
G
K
D
L
R
H
F
K
F
I
S
I
S
F
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
S1469
M
D
F
L
S
G
I
S
S
C
N
E
W
E
K
Honey Bee
Apis mellifera
XP_393800
2028
231830
A1407
P
D
F
I
N
K
V
A
E
L
D
S
D
Q
V
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
V1081
Q
A
L
N
K
F
I
V
A
E
T
K
S
E
E
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
E1066
H
A
Q
R
S
L
L
E
L
I
E
L
V
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
T1408
H
D
V
L
M
T
V
T
G
A
M
D
L
S
I
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
T1200
F
I
N
S
V
E
L
T
F
S
C
I
T
S
Q
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
E1219
M
E
S
V
K
I
R
E
L
Y
A
Q
L
L
E
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
6.6
N.A.
6.6
6.6
N.A.
N.A.
93.3
N.A.
6.6
N.A.
6.6
6.6
20
6.6
P-Site Similarity:
100
100
N.A.
6.6
N.A.
6.6
6.6
N.A.
N.A.
100
N.A.
33.3
N.A.
26.6
26.6
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
0
8
8
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% C
% Asp:
0
22
8
0
0
0
0
0
0
0
8
8
8
8
0
% D
% Glu:
0
8
0
0
0
8
0
15
8
8
8
8
0
15
15
% E
% Phe:
8
0
29
22
8
22
8
0
15
22
22
0
0
8
0
% F
% Gly:
8
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% G
% His:
15
22
22
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
8
15
0
0
15
0
15
0
0
8
% I
% Lys:
0
8
0
22
36
8
0
8
0
0
0
8
0
0
8
% K
% Leu:
22
0
15
22
0
29
36
0
15
8
0
8
15
29
43
% L
% Met:
15
0
0
0
8
0
0
0
0
0
29
22
0
0
8
% M
% Asn:
0
0
8
8
8
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
0
0
8
22
29
8
% Q
% Arg:
22
22
0
8
8
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
15
0
22
29
29
29
8
22
36
15
8
% S
% Thr:
0
0
0
0
0
8
0
15
0
0
8
0
8
0
0
% T
% Val:
0
0
8
8
8
0
15
29
22
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
15
8
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _